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dual-energy x-ray absorptiometry scanner hologic discovery dexa scanner  (Hologic Inc)

 
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    Hologic Inc dual-energy x-ray absorptiometry scanner hologic discovery dexa scanner
    Dual Energy X Ray Absorptiometry Scanner Hologic Discovery Dexa Scanner, supplied by Hologic Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dual-energy x-ray absorptiometry scanner hologic discovery dexa scanner/product/Hologic Inc
    Average 90 stars, based on 1 article reviews
    dual-energy x-ray absorptiometry scanner hologic discovery dexa scanner - by Bioz Stars, 2026-03
    90/100 stars

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    A. Airway hyperresponsiveness in genetically obese (ob/ob) and lean wild type (WT) and FABP4 and FABP5 double knockout mice (FABP4-5 KO) on a Balb/C background. Measurements were performed using the FlexiVent Fx system with the forced oscillation technique, starting at baseline and then with increasing doses of methacholine (MeCh) up to 25 mg. B. Body weights from mice used in panel A (n=4-9 per group). C. Representative DEXA scanner body composition images from obese and lean WT mice, and quantification of thoracic fat percentage in WT and FABP4 KO lean and obese (ob/ob) mice (n=3-9 per group). D. Measurement of airway hyperresponsiveness in WT lean treated with PBS (WT PBS), WT obese treated with PBS (ob/ob), WT obese (ob/ob) treated with anti-FABP4 monoclonal antibody (mAb) (n=3-8 per group). E. Plasma and F. BALF FABP4 levels from mice in panel D, measured by ELISA. G. Measurement of airway hyperresponsiveness in WT lean, FABP4 KO lean, WT obese (ob/ob), FABP4 KO obese (ob/ob), and WT obese (ob/ob) mice treated with anti-FABP4 monoclonal antibody (mAb) (n=4-7 per group).

    Journal: bioRxiv

    Article Title: An Adipo-Pulmonary Axis Mediated by FABP4 Hormone Defines a Therapeutic Target Against Obesity-Induced Airway Disease

    doi: 10.1101/2024.07.15.603433

    Figure Lengend Snippet: A. Airway hyperresponsiveness in genetically obese (ob/ob) and lean wild type (WT) and FABP4 and FABP5 double knockout mice (FABP4-5 KO) on a Balb/C background. Measurements were performed using the FlexiVent Fx system with the forced oscillation technique, starting at baseline and then with increasing doses of methacholine (MeCh) up to 25 mg. B. Body weights from mice used in panel A (n=4-9 per group). C. Representative DEXA scanner body composition images from obese and lean WT mice, and quantification of thoracic fat percentage in WT and FABP4 KO lean and obese (ob/ob) mice (n=3-9 per group). D. Measurement of airway hyperresponsiveness in WT lean treated with PBS (WT PBS), WT obese treated with PBS (ob/ob), WT obese (ob/ob) treated with anti-FABP4 monoclonal antibody (mAb) (n=3-8 per group). E. Plasma and F. BALF FABP4 levels from mice in panel D, measured by ELISA. G. Measurement of airway hyperresponsiveness in WT lean, FABP4 KO lean, WT obese (ob/ob), FABP4 KO obese (ob/ob), and WT obese (ob/ob) mice treated with anti-FABP4 monoclonal antibody (mAb) (n=4-7 per group).

    Article Snippet: Body composition was measured using a DEXA scanner (Lunar PIXImus2, GE Healthcare, Waukesha, WI) in anesthetized mice (100 mg/kg ketamine / 10 mg/kg xylazine, ip).

    Techniques: Double Knockout, Enzyme-linked Immunosorbent Assay